Fatal Coxsackievirus A-16 Pneumonitis in Adult

Complete Genome Sequence of a Coxsackievirus A16 Strain, Isolated from a Fatal Case in Shenzhen, Southern China, in 2014

We determined the complete genome sequence of a coxsackievirus A16 strain (CVA16/SZ29/CHN/2014) from a fatal case in Shenzhen, southern China, in 2014. The strain was assigned to subgenotype B1b based on phylogenetic analysis of the VP1 gene.

Fatal chemical pneumonitis due to cadmium fumes.

Acute exposure to high concentrations of cadmium fumes may cause acute chemical pneumonitis with a possibly fatal outcome. The etiologic diagnosis of acute cadmium intoxication from inhaled fumes may be difficult and can be confused with other forms of acute respiratory failure. We report on a case of a fit 53 year-old man who was exposed to cadmium fumes after flame-cutting an alloy containing...

Effect of Host Src-kinase Inhibition on Replication of Coxsackievirus B3 in vitro

Afatinib-Induced Acute Fatal Pneumonitis in Metastatic Lung Adenocarcinoma

Afatinib is an oral tyrosine kinase inhibitor (TKI) that inhibit Endothelial Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and HER4. The common side effects of EGFR TKI are rash, acne, diarrhea, stomatitis, pruritus, nausea, and loss of appetite. Drug induced pneumonitis is the less common adverse effects of EGFR TKI. Afatinib, 2nd generation EGFR TKI is antici...

Acute systemic lupus erythematosus with fatal pneumonitis and disseminated intravascular coagulation.

We reported the case of a 40-year-old female with acute onset of systemic lupus erythematosus, followed rapidly by the development of fatal pneumonitis and disseminated intravascular coagulation. The likely relationship between these events and the therapeutic options are discussed.